Preferred Name |
Peptide immunogenicity prediction |
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Synonyms |
Immunogenicity prediction Antigenicity prediction Immunogen design Hopp and Woods plotting MHC peptide immunogenicity prediction B cell peptide immunogenicity prediction |
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Definitions |
Predict antigenicity, allergenicity / immunogenicity, allergic cross-reactivity etc of peptides and proteins. This is usually done in the development of peptide-specific antibodies or multi-epitope vaccines. Methods might use sequence data (for example motifs) and / or structural data. Immunological system are cellular or humoral. In vaccine design to induces a cellular immune response, methods must search for antigens that can be recognized by the major histocompatibility complex (MHC) molecules present in T lymphocytes. If a humoral response is required, antigens for B cells must be identified. This includes methods that generate a graphical rendering of antigenicity of a protein, such as a Hopp and Woods plot. |
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ID |
http://edamontology.org/operation_0252 |
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comment |
This is usually done in the development of peptide-specific antibodies or multi-epitope vaccines. Methods might use sequence data (for example motifs) and / or structural data. Immunological system are cellular or humoral. In vaccine design to induces a cellular immune response, methods must search for antigens that can be recognized by the major histocompatibility complex (MHC) molecules present in T lymphocytes. If a humoral response is required, antigens for B cells must be identified. This includes methods that generate a graphical rendering of antigenicity of a protein, such as a Hopp and Woods plot. |
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Created in |
beta12orEarlier |
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hasBroadSynonym |
Immunogen design |
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hasDefinition |
Predict antigenicity, allergenicity / immunogenicity, allergic cross-reactivity etc of peptides and proteins. |
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hasExactSynonym |
Immunogenicity prediction Antigenicity prediction |
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hasNarrowSynonym |
Hopp and Woods plotting MHC peptide immunogenicity prediction B cell peptide immunogenicity prediction |
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inSubset | ||
label |
Peptide immunogenicity prediction |
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prefixIRI |
operation_0252 |
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prefLabel |
Peptide immunogenicity prediction |
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subClassOf |
Delete | Mapping To | Ontology | Source |
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http://edamontology.org/operation_0252 | ITO | SAME_URI | |
http://edamontology.org/operation_0252 | ITO | LOOM |