Preferred Name

Peptide immunogenicity prediction

Synonyms

Immunogenicity prediction

Antigenicity prediction

Immunogen design

Hopp and Woods plotting

MHC peptide immunogenicity prediction

B cell peptide immunogenicity prediction

Definitions

Predict antigenicity, allergenicity / immunogenicity, allergic cross-reactivity etc of peptides and proteins. This is usually done in the development of peptide-specific antibodies or multi-epitope vaccines. Methods might use sequence data (for example motifs) and / or structural data. Immunological system are cellular or humoral. In vaccine design to induces a cellular immune response, methods must search for antigens that can be recognized by the major histocompatibility complex (MHC) molecules present in T lymphocytes. If a humoral response is required, antigens for B cells must be identified. This includes methods that generate a graphical rendering of antigenicity of a protein, such as a Hopp and Woods plot.

ID

http://edamontology.org/operation_0252

comment

This is usually done in the development of peptide-specific antibodies or multi-epitope vaccines. Methods might use sequence data (for example motifs) and / or structural data.

Immunological system are cellular or humoral. In vaccine design to induces a cellular immune response, methods must search for antigens that can be recognized by the major histocompatibility complex (MHC) molecules present in T lymphocytes. If a humoral response is required, antigens for B cells must be identified.

This includes methods that generate a graphical rendering of antigenicity of a protein, such as a Hopp and Woods plot.

Created in

beta12orEarlier

hasBroadSynonym

Immunogen design

hasDefinition

Predict antigenicity, allergenicity / immunogenicity, allergic cross-reactivity etc of peptides and proteins.

hasExactSynonym

Immunogenicity prediction

Antigenicity prediction

hasNarrowSynonym

Hopp and Woods plotting

MHC peptide immunogenicity prediction

B cell peptide immunogenicity prediction

inSubset

http://edamontology.org/bio

http://edamontology.org/operations

label

Peptide immunogenicity prediction

prefixIRI

operation_0252

prefLabel

Peptide immunogenicity prediction

subClassOf

http://edamontology.org/operation_0250

http://edamontology.org/operation_1777

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