EDAM - Bioscientific data analysis ontology

Last uploaded: February 26, 2021
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Preferred Name

Phylogenetic footprinting
Synonyms

Phylogenetic shadowing
Definitions

Comparison of a DNA sequence to orthologous sequences in different species and inference of a phylogenetic tree, in order to identify regulatory elements such as transcription factor binding sites (TFBS). Phylogenetic shadowing is a type of footprinting where many closely related species are used. A phylogenetic 'shadow' represents the additive differences between individual sequences. By masking or 'shadowing' variable positions a conserved sequence is produced with few or none of the variations, which is then compared to the sequences of interest to identify significant regions of conservation.
ID

http://edamontology.org/operation_0327
comment

Phylogenetic shadowing is a type of footprinting where many closely related species are used. A phylogenetic 'shadow' represents the additive differences between individual sequences. By masking or 'shadowing' variable positions a conserved sequence is produced with few or none of the variations, which is then compared to the sequences of interest to identify significant regions of conservation.
Created in

beta12orEarlier
hasDefinition

Comparison of a DNA sequence to orthologous sequences in different species and inference of a phylogenetic tree, in order to identify regulatory elements such as transcription factor binding sites (TFBS).
hasNarrowSynonym

Phylogenetic shadowing
inSubset

http://edamontology.org/bio

http://edamontology.org/operations
label

Phylogenetic footprinting
prefixIRI

operation_0327
prefLabel

Phylogenetic footprinting
seeAlso

https://en.wikipedia.org/wiki/Phylogenetic_footprinting
subClassOf

http://edamontology.org/operation_0323
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