Preferred Name |
Haplotype mapping |
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Synonyms |
Haplotype reconstruction Haplotype map generation Haplotype inference |
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Definitions |
Infer haplotypes, either alleles at multiple loci that are transmitted together on the same chromosome, or a set of single nucleotide polymorphisms (SNPs) on a single chromatid that are statistically associated. Haplotype inference can help in population genetic studies and the identification of complex disease genes, , and is typically based on aligned single nucleotide polymorphism (SNP) fragments. Haplotype comparison is a useful way to characterize the genetic variation between individuals. An individual's haplotype describes which nucleotide base occurs at each position for a set of common SNPs. Tools might use combinatorial functions (for example parsimony) or a likelihood function or model with optimisation such as minimum error correction (MEC) model, expectation-maximisation algorithm (EM), genetic algorithm or Markov chain Monte Carlo (MCMC). |
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ID |
http://edamontology.org/operation_0487 |
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comment |
Haplotype inference can help in population genetic studies and the identification of complex disease genes, , and is typically based on aligned single nucleotide polymorphism (SNP) fragments. Haplotype comparison is a useful way to characterize the genetic variation between individuals. An individual's haplotype describes which nucleotide base occurs at each position for a set of common SNPs. Tools might use combinatorial functions (for example parsimony) or a likelihood function or model with optimisation such as minimum error correction (MEC) model, expectation-maximisation algorithm (EM), genetic algorithm or Markov chain Monte Carlo (MCMC). |
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Created in |
beta12orEarlier |
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hasDefinition |
Infer haplotypes, either alleles at multiple loci that are transmitted together on the same chromosome, or a set of single nucleotide polymorphisms (SNPs) on a single chromatid that are statistically associated. |
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hasExactSynonym |
Haplotype reconstruction Haplotype map generation Haplotype inference |
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inSubset | ||
label |
Haplotype mapping |
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prefixIRI |
operation_0487 |
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prefLabel |
Haplotype mapping |
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subClassOf |
Delete | Mapping To | Ontology | Source |
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http://edamontology.org/operation_0487 | ITO | SAME_URI | |
http://edamontology.org/operation_0487 | ITO | LOOM |