EDAM - Bioscientific data analysis ontology

Last uploaded: February 26, 2021
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Preferred Name

Gene-set enrichment analysis
Synonyms

Gene-set over-represenation analysis

Functional enrichment analysis

GSEA

Gene set testing

Gene Ontology term enrichment

Gene Ontology concept enrichment

GO-term enrichment

Gene set analysis
Definitions

Identify classes of genes or proteins that are over or under-represented in a large set of genes or proteins. For example analysis of a set of genes corresponding to a gene expression profile, annotated with Gene Ontology (GO) concepts, where eventual over-/under-representation of certain GO concept within the studied set of genes is revealed. "Gene set analysis" (often used interchangeably or in an overlapping sense with "gene-set enrichment analysis") refers to the functional analysis (term enrichment) of a differentially expressed set of genes, rather than all genes analysed. Analyse gene expression patterns to identify sets of genes that are associated with a specific trait, condition, clinical outcome etc. Gene sets can be defined beforehand by biological function, chromosome locations and so on. The Gene Ontology (GO) is typically used, the input is a set of Gene IDs, and the output of the analysis is typically a ranked list of GO concepts, each associated with a p-value.
ID

http://edamontology.org/operation_2436
comment

"Gene set analysis" (often used interchangeably or in an overlapping sense with "gene-set enrichment analysis") refers to the functional analysis (term enrichment) of a differentially expressed set of genes, rather than all genes analysed.

Analyse gene expression patterns to identify sets of genes that are associated with a specific trait, condition, clinical outcome etc.

Gene sets can be defined beforehand by biological function, chromosome locations and so on.

The Gene Ontology (GO) is typically used, the input is a set of Gene IDs, and the output of the analysis is typically a ranked list of GO concepts, each associated with a p-value.
Created in

beta12orEarlier
hasBroadSynonym

Gene set testing
hasDefinition

Identify classes of genes or proteins that are over or under-represented in a large set of genes or proteins. For example analysis of a set of genes corresponding to a gene expression profile, annotated with Gene Ontology (GO) concepts, where eventual over-/under-representation of certain GO concept within the studied set of genes is revealed.
hasExactSynonym

Gene-set over-represenation analysis

Functional enrichment analysis

GSEA
hasNarrowSynonym

Gene set analysis
hasRelatedSynonym

Gene Ontology term enrichment

Gene Ontology concept enrichment

GO-term enrichment
inSubset

http://edamontology.org/bio

http://edamontology.org/operations
label

Gene-set enrichment analysis
prefixIRI

operation_2436
prefLabel

Gene-set enrichment analysis
seeAlso

https://en.wikipedia.org/wiki/Gene_Ontology_Term_Enrichment

https://en.wikipedia.org/wiki/Gene_set_enrichment_analysis
subClassOf

http://edamontology.org/operation_2495

http://edamontology.org/operation_3501
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