EDAM - Bioscientific data analysis ontology

Last uploaded: February 26, 2021
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Preferred Name

Peak calling
Synonyms

Protein binding peak detection

Peak-pair calling
Definitions

Identify putative protein-binding regions in a genome sequence from analysis of Chip-sequencing data or ChIP-on-chip data. Chip-sequencing combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to generate a set of reads, which are aligned to a genome sequence. The enriched areas contain the binding sites of DNA-associated proteins. For example, a transcription factor binding site. ChIP-on-chip in contrast combines chromatin immunoprecipitation ('ChIP') with microarray ('chip'). "Peak-pair calling" is similar to "Peak calling" in the context of ChIP-exo.
ID

http://edamontology.org/operation_3222
comment

Chip-sequencing combines chromatin immunoprecipitation (ChIP) with massively parallel DNA sequencing to generate a set of reads, which are aligned to a genome sequence. The enriched areas contain the binding sites of DNA-associated proteins. For example, a transcription factor binding site. ChIP-on-chip in contrast combines chromatin immunoprecipitation ('ChIP') with microarray ('chip'). "Peak-pair calling" is similar to "Peak calling" in the context of ChIP-exo.
Created in

1.1
hasDefinition

Identify putative protein-binding regions in a genome sequence from analysis of Chip-sequencing data or ChIP-on-chip data.
hasExactSynonym

Protein binding peak detection
hasNarrowSynonym

Peak-pair calling
inSubset

http://edamontology.org/bio

http://edamontology.org/operations
label

Peak calling
prefixIRI

operation_3222
prefLabel

Peak calling
subClassOf

http://edamontology.org/operation_0415
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