Preferred Name |
Protein folds and structural domains |
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Synonyms |
Protein folds Protein membrane regions Intramembrane regions Protein topological domains Protein structural domains Protein transmembrane regions Protein domains Transmembrane regions |
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Definitions |
Protein tertiary structural domains and folds in a protein or polypeptide chain. This includes topological domains such as cytoplasmic regions in a protein. This includes trans- or intra-membrane regions of a protein, typically describing physicochemical properties of the secondary structure elements. For example, the location and size of the membrane spanning segments and intervening loop regions, transmembrane region IN/OUT orientation relative to the membrane, plus the following data for each amino acid: A Z-coordinate (the distance to the membrane center), the free energy of membrane insertion (calculated in a sliding window over the sequence) and a reliability score. The z-coordinate implies information about re-entrant helices, interfacial helices, the tilt of a transmembrane helix and loop lengths. |
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ID |
http://edamontology.org/topic_0736 |
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comment |
This includes topological domains such as cytoplasmic regions in a protein. This includes trans- or intra-membrane regions of a protein, typically describing physicochemical properties of the secondary structure elements. For example, the location and size of the membrane spanning segments and intervening loop regions, transmembrane region IN/OUT orientation relative to the membrane, plus the following data for each amino acid: A Z-coordinate (the distance to the membrane center), the free energy of membrane insertion (calculated in a sliding window over the sequence) and a reliability score. The z-coordinate implies information about re-entrant helices, interfacial helices, the tilt of a transmembrane helix and loop lengths. |
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Created in |
beta12orEarlier |
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hasDefinition |
Protein tertiary structural domains and folds in a protein or polypeptide chain. |
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hasHumanReadableId |
Protein_folds_and_structural_domains |
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hasNarrowSynonym |
Protein folds Protein membrane regions Intramembrane regions Protein topological domains Protein structural domains Protein transmembrane regions Protein domains Transmembrane regions |
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inSubset | ||
isdebtag |
true |
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label |
Protein folds and structural domains |
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prefixIRI |
topic_0736 |
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prefLabel |
Protein folds and structural domains |
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seeAlso | ||
subClassOf |
Delete | Mapping To | Ontology | Source |
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http://edamontology.org/topic_0736 | BERO | SAME_URI | |
http://edamontology.org/topic_0736 | ITO | SAME_URI | |
http://edamontology.org/topic_0736 | BMT | SAME_URI | |
http://edamontology.org/topic_0736 | BERO | LOOM | |
http://edamontology.org/topic_0736 | ITO | LOOM |